HUN 4446 Exam 2 Study Guide
Lactose Mal Digestion/ Malabsorption
1. What are the products of lactose digestion? -The products of lactose digestion are glucose and galactose.
2. What is lactase deficiency? -Lactase deficiency is a deficiency in the enzyme that breaks down lactose. The causes of lactase deficiency include congenital defects, secondary lactase deficiency, and primary (acquired).
3. Define lactose maldigestion, identify the potential etiologies of lactose maldigestion, and describe the metabolic/physiologic effects of lactose maldigestion. -Lactose Maldigestion: reduced digestion of lactose due to low lactase activity that subsequently results in MALABSORBTION of lactose; it may be asymptomatic. - The …show more content…

7. How does Crohn’s disease affect nutritional status/ requirements? What factors contribute to the risk of altered nutritional status? -Weight loss is common in Crohn’s disease due to ↑ requirements and ↓ oral intake -Bacterial overgrowth, resection, and ileal involvement all lead to malabsorption and ↓ availability, which leads to ↑ nutrient losses. If bile cannot be reabsorbed in the ileum, fat and fat soluble vitamins would be malabsorbed. B12 is also largely absorbed in the ileum, so that, too, would be ↓.
8. Identify medications (generic names) used to treat Crohn’s disease and the nutritionally relevant side effects of specific drugs discussed in class (i.e. sulfasalazine, methotrexate, prednisone). -The generic names for the medications used to treat Crohn’s disease are mesalamin and sulfasalazine (which are 5-aminosalicylic [5-ASA] drugs); metronidazole and ciproflaxen (which are antibiotics), prednisone (which is a corticosteroid); azathioprine, methrotrexate, and 6-mercaptopurine (which are steroid sparing immunosuppressants); infliximab and adalimumab (which are biological therapies); cholestyramine (a diarrheal agent). -Sulfasalazine, a 5-ASA, is typically used in Crohn’s disease that has ileal and colon involvement. Take with 8oz of water after meals or with food, take iron and/or folate separately. Make sure you are adequately hydrated;